Many EECS students probably should only take EECS 381 as a general credit course during senior and fill out the 16 ULCS first with other EECS classes. I’ve known people who even take EECS 482 and found out they fail the day before graduation.
If you have at least a A- among each of 280, 203, 281, 370, and 376, then you have a good indicator that you can handle 381