What field are you in or what type of courses are you looking to take? Number one rule when looking for online courses is that they are only good if they are accredited.
I looked into the University of Phoenix when I first started searching for an online program but ended up deciding on Unitek College in California because of the nursing programs they are known for. They have a terrific online rn to bsn program and had a number I could call in and talk to an instructor if I had questions. If I wanted to meet with someone to discuss something in person that option was available also.
Make sure you really look into each program, call the school and find out if the online program they offer comes with a tutor or someone you can quickly call when you have questions as that is very important.