^^It’s true that science published in “the most important journals” usually doesn’t come from LACs. It’s equally true that the authors of science published in “the most important journals” are NOT undergraduate students at ANY college/university.
As an undergraduate, I think the most important thing is to “learn how to do science”; whatever the question may be is secondary. Choosing a graduate school is an entirely different question.
BTW, choosing the right lab for your posdoc is of the most importance for your scientific career.
As you can see, it’s a long journey.