Consider a direct flight JFK to BUR (Burbank/Pasadena) . So much easier.
And I agree with the above suggestion–at least one night in Pasadena (if you fly into Burbank, spend the entire time in Pasadena)
http://www.marriott.com/hotels/travel/laxot-courtyard-los-angeles-pasadena-old-town/
This hotel is close to the freeway, old town restaurants, and easy access to metro rail.
r