Do I have a prayer to get into any of these colleges despite my school's disadvantages?

They aren’t going to penalize you if you are an otherwise good student because of your school. The GC sends to the schools you are applying to a school profile and oftentimes schools have regional admissions counselors familiar with the different high schools students are applying from. This is to give them context and understand some of the limitations of your school, but it doesn’t necessarily count against you. I had two friends with graduating classes less than 60 and they both ended up the same place I did, one of them even got into an IV but chose to come here instead