This - like everything else - will vary. But MV can be helpful if going into a STEM field whether credit is given or not. I spoke to an AO at a top 50 LAC recently - she said DE courses taught at the HS won’t count. DS2 takes DE classes on campus of a local top 50 university with college students - she said they may transfer. Another top 50 private university we visited has a cap on number of DE credits, and they will only accept classes that are not required for HS graduation. DS1 is at a top 25 private university - they took AP for a few gen ed requirements and for placement. They are in a box on his college transcript, but don’t count for much.