<p>I am a HS senior. This year, I took BC Calculus and most likely ended up with a C for this semester (the highest possible it could be is a B). I did not have AB first.</p>
<p>I have heard that med schools will look at your high school grades to make sure you weren't slacking off then. If the rest of your transcript is solid (especially the sciences) and as long as you do well on the AP (4 or 5), will they really care that much?</p>