How badly would getting a C hurt?

<p>Unfortunately, unless I can do something fast (I'm trying..) I may get a C in AP Chemistry. I got a B first term, but if I get a C second term.. it may average to a C. I'm hoping I don't, but just in case.. how would it hurt my chances to Duke or Vandy?
Edit - I'm a senior applying RD, so I can't really.. do much 3rd or 4th term to pull it up if I do get one.</p>

<p>It may hurt a bit, but if your other grades are strong it shouldn’t make much of a difference.</p>