How difficult is it to get at least a 3.5 science GPA with a Bio Major?

Hello, I am am wondering how difficult it is to maintain at least a 3.5 science GPA with a biology major. I plan on taking no more than 2 science classes (discounting math) per semester for Penn. I also plan on taking only math 104 and statistics my first and second semesters respectively.

Thanks.

@nines99 if you keep your workload light, i.e. 4 classes a semester and no more than 2 being science classes it is not that hard, provided you are meticulous and proactive about your studying, you attend class, go to office hours etc.