How important is the mid-year report?

I understand that it is the most important document that you send to college (next to the common app) in determining your admission. But to what extent does the mid-year report matter? I’m taking 6 AP classes (which I kind of regret) and so far I have a 95 GPA. All my grades are in the 90’s with the exception of AP Chem and AP Stats (which I have 70’s in). I’m not too worried about chem because my teacher is infamous in the school for giving an extremely difficult curriculum. However, I’m more worried about stats. Would these two 70’s severely affect my chances of getting into my top colleges?