Inside Medicine. What Are You Seeing? [COVID-19 medical news]

Fauci says there are incoming autopsy studies that will answer this question about virus in organs.

Well, unfortunately, the anti-vaxxers won’t want one so count them out.

Fauci says there are incoming studies that shed light on transmission to and from children as well.

It’s not just the antivaxxers
 One of my family members is a type 1 diabetic. Long term effects of the vaccine are currently unknown and unstudied, so they won’t get it yet
too risky. The rest of us all will.

Chilean police dogs being trained to sniff out Covid-19 in humans
From CNN’s Tatiana Arias and Cristopher Ulloa

Police dogs in Chile are being trained to detect Covid-19 in humans by sniffing their sweat.

Chile’s National Police and the Catholic University of Chile are working on a joint project to train three golden retrievers and a labrador to detect “a new odor" in humans which in this case belong to Covid-19 patients, the university’s professor and veterinary epidemiologist, Fernando Mardones told CNN’s Spanish-language news network, CNN en Español.

“The selected dogs have years working on the detection of drugs, explosives and other types of things. For them, it is simply learning to detect a new smell, a new aroma,” Mardones said.
Coronavirus does not have a smell per se, but sweat does and dogs can be trained to detect the smell of a person going through an infection process, Mardones explained.

“A body that contracts Covid-19 generates volatile organic compounds. A sample is taken from a person in the early stages of the infection. A gauze is left for about 15 minutes on an individual’s underarm. That’s the sample we store and use to train the dogs with,” Mardones explained.

The “bio-detector” dogs, as they are called by the Chilean police, are expected to be trained by mid-September and sent to places with high concentrations of people – such as malls, sports centers, bus terminals and airports, according to the Chilean police.

A dog can smell 250 people in an hour, so they can be deployed when these places reopen," Julio Santelices from the Chilean police said.

“Their olfactory capacity is so great that they would be able to detect the disease early on” Santelices said, adding that “this means that an asymptomatic person could be detected by the bio-detector dog.”

The dogs can take from two weeks up to two months to be fully trained. The canines are being taught to sit next to the individual with the Covid-19 virus they have detected, instead of “pawing” the individual as they currently do when sniffing drugs, the Chilean police told CNN.

I think there might be many individuals of different ages, profiles, with certain health conditions, etc. who might choose not to get the vaccine (or to wait awhile), assuming one launches with limited (or no) long-term safety data.

It’s reasonable that a lack of long-term safety data would make one think carefully about getting any vaccine (or treatment), especially the developmental vaccines that are based on novel technologies (AZ/Oxford, Moderna, probably a few more).

So much will depend on the make-up of the Phase III volunteer pools (assuming efficacy is proven)
for example, if there aren’t many 70+ year old patients in the study, that could lead elderly people to choose not to get the vaccine (or their docs to advise against it), especially early on. No/few patients in the study with auto-immune diseases? Type 1 Diabetes? Etc. Etc.

If in-person school is a goal, then teachers and other school employees should be in the vaccine line after health workers


50 million is a lot. That is almost 20% of populations. How many health workers are there, teachers, military, etc? We can cover them all and will still have plenty left over for other risk groups in the first round. In the meantime, other vaccines will become available.

@Iglooo - I tend to agree.

Though timing/planning will be key. I hope they can roll it out! I remember in 2009 that the H1N1 vaccine came to my school (vaccinating teachers) about three months after I’d gotten the disease (still got the vaccine just in case).

From what I read, they are working on the roll out, getting enough glass virals and syringes made, building distribution networks. It will still be chaotic.

Vaccines stoke the immune system, so when you have an autoimmune disorder (immune system attacking one’s own body) then vaccines can cause some symptoms. (Actually type 1 diabetes is an autoimmune disorder.) I have lupus and my kid has type 1 but our doctors still l recommend vaccines. Can someone explain why we should avoid the possible vaccine for COVID ?

It would be very risky to have all the medical workers to get the vaccine when it rolls out given that it has gone through an expedited process. I would hate to see all get the vaccine and after a period of time passes it is discovered the new vaccine has harmful effects and all of our trained healthcare force is incapacitated. Obviously a worse case scenario but still it would be prudent to not have them all vaccinated immediately.

I just volunteered to participate in a vaccine study. Not sure I have enough external contacts daily to qualify, the screening questions seemed to indicate a preference for those who are still employed or who live in crowded housing. But if they need volunteers over 60 they may have to accept some of us suburban retirees.

Trial volunteers can’t be the shelter in place types. If enough people in the placebo group don’t get infected, it will be difficult for the vaccine to demonstrate efficacy. Hence, the focus on those who are going to work be it in healthcare, or at a grocery store, or having other external contacts.

That is something for you to talk with your family’s doctor(s) about.

I am shelter in place most of the time but I do air travel about once or twice a month. Would I make a decent volunteer?

Only the clinical trial investigators can make that determination. You can take a look at the inclusion/exclusion criteria for specific drug/vaccine trials at clinicaltrials.gov.

Here is Moderna’s Phase 3 vaccine protocol for mRNA-1273, scroll down to the Inclusion Criteria section, the first criterion is:

Looking at the exclusion criteria, one can see that some people with certain auto-immune diseases won’t qualify (so this trial, by design, will not demonstrate efficacy or safety in these types of patients).

https://www.clinicaltrials.gov/ct2/show/NCT04470427?cond=covid-19+vaccine&phase=2&draw=2&rank=1

One can search for the other vaccine (or therapeutic) trials at this site to research those inclusion/exclusion criteria.

Find more information on covid-19 research studies here, where you can also sign-up to be screened as a volunteer:
https://www.coronaviruspreventionnetwork.org/

I’m not shelter in place (which as Gov Cuomo has pointed out, is the wrong term anyway. SIP is for active shooter situations, NY order was stay at home.) I’m mostly stay at home, but do go out to stores and have some light contact with others. But no, I understand that I’m not at as high a risk of infection as many others, and that that fact might reduce the likelihood I get selected.

@MomofJandL - I’m in the same boat, but did register in case they need me.

My sister-in-law is one of them. And knowing her, she will convince her husband and three adult children not to get the vaccine, either. Sigh.