Wasn’t this discussed on another thread? For pre-med or CE, when the class is available, top colleges (which you mentioned before) can look for the full set: AP bio (or equivalent,) AP chem, AP physics. This isn’t only about what your young friend chose to take, but the thousands of other applicants who will have all 3. You can’t compare to another success story without knowing the other person’s fuller details.
But taking in 12th. That’s fine. Adcoms will see the mid year report. Not all schools have schedules that allow a kid to take everything they need before 12th.