<p>Region is only relevant for your first job hiring. When you are talking about math and engineering, you will (most likely) have internships and other experiences before you graduate and will likely start working for a regional firm. From there it is more about your work experience and where your degree is from holds less weight.</p>
<p>Ohio State is not a regional school. That would be like asking if people on the west coast will recognize MIT or people on the east coast would respect UCLA. </p>