@Gumbymom would know for sure, but that’s always been my understanding. For the CSUs I think a college class can count for two terms, but I don’t believe the UCs allow that. Failing to meet the a-g requirements will result in an automatic rejection from all CA publics.
I would pick a CSU that you like that isn’t Cal Poly (it’s generally not a safety, it can be a match if you find it attractive) for a safety. Remember, medical schools do not care about the “prestige” of your undergraduate degree. They care about GPA, MCAT, volunteering and letters. A CSU would have the added bonus of being cheaper than a UC.
Lastly, I agree, don’t be a biology major. Pick something more employable if medical school doesn’t work. Forty percent of those who apply get in, but many never even get that far in the process.
Good luck and keep up the hard work.