Is that $50k for $200k pre-tax or post-tax income? If it’s pre-tax then that’s just ridiculous! Middle class families, i.e. most of us, have the hardest time paying for college. If you are rich it doesn’t matter because you can afford it; If you are poor, it doesn’t matter either as you can get a free ride most anywhere. But if you are neither rich nor poor, you pay through the nose!
It sounds like the OP’s daughter might be interested in med school? If that’s the case she’d want to get through undergrad as inexpensively as possible. Especially if OP has other children in the pipeline, I would avoid all private schools like a plague. Even with “generous” financial aid, most of these schools will still end up costing a fortune, as their aid will mostly come in the form of loans. The last thing OP would want is to saddle her daughter with loans before grad/med school. A degree in Neurology/neuroscience/biology does not have the best job prospects. The pay is also quite low. You almost need to go on to grad/med school to get a well paying job.
I would consider first and foremost the in-state public university options. Many public universities have scholarships that they do not go out of their way to advertise, but are available to in-students who earn good grades. Next, research state U’s in neighboring states that often have tuition discount agreements with your state. Staying within driving distance also lowers cost for traveling to/from home for the holidays, breaks, summer. Last look to OOS publics that offer good merit aid to top OOS students, such as University of Alabama.
If the OP’s home state is MA, then UMass-Amherst should be the top choice, followed by UMass in other locales.
For OOS options in neighboring states, I would consider:
U of VT
SUNY-Binghamton
U of CT
U of DE
All are considered part of the “Public Ivies” (top 30 flagship state U’s) if you care about such things.
https://en.wikipedia.org/wiki/Public_Ivy