What is generally considered a "safe harbor" against admission rescission?

I figure an A student can get a couple of B’s and B student can get a couple of C’s. If you want to drop a course, you must call the college and find out if they care. But really, my kids didn’t find the pace of senior year that bad - and the second half of it you are no longer trying to juggle applications. My younger son slacked off a bit in some of his AP courses when he realized that he wasn’t going to get credit for more than 5 and he already had the fives. He didn’t do disastrously on the APs, but the lack of extra studying did show in his scores. (mostly 4’s instead of all 5’s).