Moderna describes vaccine-induced antibody neutralization response to several variants of COVID-19, based on sera from 8 vaccinated individuals.
https://investors.modernatx.com/news-releases/news-release-details/moderna-provides-clinical-update-neutralizing-activity-its-covid
Note that this is similar to what J&J - Janssen described (linked in post #3205).
Summary of neutralization reduction (N-fold) compared to ancestral variant (higher number = greater reduction in neutralization = greater risk of vaccine being less effective):
Variant | Greek Letter | Moderna | J&J - Jannsen |
---|---|---|---|
B.1.1.7 | Alpha | ~1 | 0.9 |
B.1.351 | Beta | 7.3-8.4 | 3.6 |
P.1 | Gamma | 3.2 | 3.4 |
B.1.617.2 | Delta | 2.1 | 1.6 |
B.1.525 | Eta | 4.2 | |
B.1.617.1 | Kappa | 3.3-3.4 | |
A.23.1 | ~1 | ||
A.VOI.V2 | 8.0 | ||
B.1.617 | 1.5 | ||
P.2 | 2.2 |