Allergies could also mask minor COVID-19 symptoms. People who get stuffy or runny noses all the time due to allergies may not notice anything unusual if they get stuffy or runny noses due to minor cases of COVID-19.
I will say Iāve thought about this for awhile that I donāt think we truly know all there is to know and I do think we will find there is a gene that people have that make them get it/not get it. I know plenty unvax who either never got it or barely had a sniffle and had it as well as some who have every single shot and booster and keep getting it as well as have been very sick. And in all those cases, the masks didnāt seem to impact it either way.
Super dodger here 
Keeping 
while touching 
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Iāve been lucky indeed. Hubby and one daughter had it twice each and my other daughter once. Fingers crossed I stay lucky!
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We think S had it, although he was not ill. The reason we think he had it is that he had a long Covid symptom (excessive thirst/urination but complete labs show no reason). It came & went away out of the blue. He has very bad allergies to trees, grass, mold & dust.
H, D, SIL & I never had it ā¦ until we suddenly did a few weeks ago. D & GD got it at the same time, and the only place they could have gotten it was at an outside community pool. I got it a couple days later ā¦ SIL a couple days after me ā¦ and H a couple days after him. H & I had just dodged an outbreak that started at our table at a wedding a couple weeks prior (we were the only ones who had no symptoms & never tested positive). But SILās parents, who are over 65, never got it - even though they babysat GD the day before she got a fever.
A guy we know had very close exposure to his wife & didnāt get it ā¦ and later very close in-the-car-for-a-couple-days exposure to his dad who got it ā¦ but the guy never got it. And a friend got Covid on vacation, and despite the fact that her H had no choice but to be with her during her quarantine, he never got it.
I figure some folks donāt get it. Until they do!
So you haven't yet caught COVID. Does that make you a superdodger? : Goats and Soda : NPR mentions that there is an HLA mutation that appears to be in 1 in 10 people and 1 in 5 who had asymptomatic COVID-19.
The relevant research paper is here: https://www.medrxiv.org/content/10.1101/2021.05.13.21257065v2 . The relevant mutation is HLA-B*15:01, and the effect is even stronger if HLA-DRB1*04:01 is also present.
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To the best of our knowledge, husband, son, brother and SIL, and niece and nephew (altogether in five different parts of the country) have never shown any symptoms nor tested positive. Everybody, especially immunocompromised brother, have been very careful all along.
Interestingly, son in Seattle had a bad bout of presumed flu in early February 2020. He did see a doctor but they didnāt test for flu; just presumed. Since that was the initial breakout locale, and since the researchers subsequently established via old samples that the virus had been circulating in the area even before 2020, he might have had it. No long COVID symptoms whatsoever. We may never know for sure.
As far as I know, most of my family hasnāt gotten it. This includes me, H, D, Dās husband and kids, my sister, my brother, my Hās aunts,and my aunt in assisted living.
My S and his GF went out one time last March and got it (everyone in the group did.) Most of my Hās extended family, much less cautious than us, have gotten it.
I had a pretty bad cold early this summer, which I am sure I caught from grandkids as that whole family had it too. We all tested multiple times, including PCRās, and no one tested positive so I assume it was something else, though at the time I wouldnāt have been surprised if it had been Covid.
I found this very interesting. Large study, 1.5 million. Shows a correlation between time of day one receives the vaccine and subsequent effectiveness. Wondering if those here who remain COVID free were vaccinated at those times of day which are apparently more efficient.
https://www.jci.org/articles/view/167339
RESULTS. Breakthrough infections differed based on vaccination time, with lowest rates associated with late morning to early afternoon, and highest rates with evening vaccination.ā
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Note that the study involved almost all (>98%) Pfizer vaccine.
My Pfizerās were fairly consistently early afternoon (I typically try to get the time slot when the Pharmacist gets back from lunch - this way, there are less cumulative delays).
That is interesting. But I would have liked to see them control for workplace. Those who were having to go to a workplace with other people seem to me to have been both more likely to be vaccinated in the evening and to be exposed more often. But I could be wrong. It would be interesting to know.
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I had Pfizer vaccines. The first two were in the late morning & the third was in the early evening. I got Covid 7-8 months after the evening shot. Iāve since had another late morning vaccine, havenāt had Covid again. Who knows?
All 4 of my COVID shots (all moderna) were at 12:30/1pm and I havenāt had COVID yet (as far as I know).
My husband and I havenāt had Covid (havenāt tested positive on any antigen tests), and had 3/4 pfizer, at a mix of times of day. We did wait just over a year from previous to get omicron booster.
We were exposed to two of our kids for sure, and maybe a couple others (though the kids were the real exposures).
It looks like this time-of-day effect has been observed with another COVID-19 vaccine (Sinopharm BBIBP-CorV, an inactivated virus vaccine):
https://www.nature.com/articles/s41422-021-00541-6
It has also been observed with vaccines against other infections:
https://www.jci.org/articles/view/133934
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