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Shouldn't we spend the money we pour into finding the origin of life instead into more beneficial research?
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<p>surprisingly, I agree with you there, because I'm a NIH employee, and I've been seeing some budget cutbacks, and since NIH is going much more into biodefense, that means less money for people like me in basic research or people who are in other things like process development.</p>
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Those antibiotics were discovered without having to rely on evolutionary theory
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<p>Yeah, I know that, I was running a fever, lightheaded, and I had no idea what I was doing, so I'll say, whoops!</p>
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Nothing in biology makes sense if evolution never occurs
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<p>I say that because I do believe in evolution. How could proteins develop an entire complex coding system dedicated to their production? How did anything develop?</p>
<p>You may argue that God created everything, but I don't see any concrete scientific evidence that He did.</p>
<p>One example of short-term evolution: the HIV virus. It's well known for its ability to mutate rapidly, hence our inability to develop a useful vaccine. However, there do exist biopharmaceuticals that can block HIV infection (I work with one of them in my lab). Let us assume for the sake of argument that "pill X" was a successful biopharmaceutical that attached to the HIV's gp120 binding site and therefore, prevented the virus particle from attaching to a T-cell.</p>
<p>Well, pill X can't just simply attach to gp120, it has to attach to something on gp120, like a specific carbohydrate configuration in the gp120 glycoprotein.</p>
<p>There is a certain carbohydrate configuration that pill X attaches to. It's a very fundamental one found in 99% of all HIV viral particles. pill X is given to infected people all over the world, and HIV is nearly eradicated. However, that 1% were somehow mutants from the rest and were able to resist pill X still, and that 1% can spread out and infect others.</p>
<p>1% may nto sound like much, but since around 40 million people are infected worldwide, 1% is still a good chunk. Some of those people are still having sex thinking they're cured... some might not even know they had the virus to begin with. In fact, 25% of infected Americans do not know of their infection.</p>
<p>Anyway, HIV has now evolved to a different glycoprotein structure.</p>
<p>And even though the above situation is hypothetical, I based it off of real events:</p>
<p>3 years ago my current supervisor developed something called CV-N which does exactly what I described above: binds to the gp120 carbohydrate configuration. To test the efficacy of CV-N on various mutants, we had another lab group develop mutant after mutant after mutant of HIV. There was in fact, one mutant that resisted CV-N.</p>