I don’t believe Case admits by major.
That said, Case has become unpredictable in recent years. Lots of high stats kids are rejected. Case was a popular choice for my D’s HS and we saw lots of unexpected outcomes. I’d categorize it as a low reach/high match for this OP.
I just looked it up. They don’t. Students declare after admission.
And Case makes it very easy to switch majors, double major… there seems to be a lot of flexibility, which could be important to many.
I agree about the unpredictability of admissions for high stats students. Demonstrated interest is important for all, but especially for students Case may seem as a likely admit based on stats. Case likes to protect their yield.
I think that is certainly an important caveat for all schools. It’s important to know what schools are looking for beyond stats and ECs. Sometimes that is expressly stated. Sometimes it isn’t.
Case has a page of requirements and enhancements. Add to that their known fondness for demonstrated interest. If the OP follows those requirements and suggestions, they should be a strong candidate.
I completely agree. An applicant who appears to be overqualified, not only by stats but also by other measures, and who may, in the mind of CWRU admissions, potentially have better options elsewhere, is likely to be deferred and/or waitlisted, particularly if s/he is from a different region, unless s/he applies (or switches to) ED/ED2, or to one of its pre-professional programs.
The CDS you are looking at is for Class of 2025. Class of 2026’s acceptance rate was 25% as I noted above. I also agree with momofboiler’s point about CWRU’s unpredictability…plenty top stats students are not accepted.
This is splitting hairs, but the very last CDS published, 2021-2022 has a 30% acceptance rate.
The bigger point is, there is a path into CWRU, it involves crossing all the T’s, dotting all the I’s, and demonstrating strong interest. To say a kid that is above the 75th percentile in SAT and above the 90th percentile in GPA, has a low chance of admission, flies in the face of the reality of the CDS.
It’s important to be using the most recent data, which is for class of 2026. Regardless, I will stick with my recent experiences with CWRU, as well as that of other posters, when sharing my perspective.
Looking up the thread, @AustenNut’s “Low Probability” category has a range of 20-39%. For CWRU, it does seem like the higher end of this range, 30%-39%ish, may be accurate even for the highest stat applicants. This isn’t a likely school for anyone, because admission is so unpredictable. You can’t just have high stats and do X, Y, Z in order to demonstrate interest. If you look at the CWRU threads, you will see plenty of high stats kids deferred or denied, including kids who did everything right and demonstrated strong genuine interest, saw this as their first choice school and were really surprised not to be admitted. You will also see some high stats kids accepted, along with some medium stat admits like my kid (1460 SAT, which I think is below average for CWRU admits).
It feels like an unpredictable high match / low reach for all of these applicants… although that is just my unscientific feeling. And yes, it’s probably changed a lot since your son was admitted in 2014. Many schools in this selectivity range have a very different admissions profile now.
I have yet to find category names for the least likely categories (20-39% and less than 20%). At one point I used less likely and unlikely and someone had suggested switching to low probability and lower probability. I am certainly open to suggestions for alternative labels. But that is why I put the percentages there, so people know how I’m trying to use the words.
With respect to Case Western, its history of yield protection and/or general uncertainty combined with a popular intended major (although CWRU does not admit by major) made me think that the overall admissions percentage was likely a good fit for this student. Although OP’s stats are higher than the 75th percentile, that is not always favorable for Case. As mentioned above, however, I am not an expert and this is just one random person’s opinion. It’s unlikely to be worth more than you paid for it. 
Someone just posted the COA. $86k full pay (I know many get merit).
I personally think your free opinion is more worthy and I suspect most agree, given their 16% yield (lower when you take out ED).
Son had the same experience with CWRU in 2018, opened every email, attended online events etc. But the admitted student event we attended in San Jose was somewhat depressing and we left early, it was seemingly all STEM students who had failed to get into top UCs. The yield protection is hardly surprising given how low their yield is.
It is hard for me to reconcile 16% yield with yield protection. If they practice it, they aren’t very good at it. It’s hard to reject all the high stats applicants and still have a 75th percentile SAT of 1520. There’s usually more to the story with numbers like that.
I think they aren’t very good at it, but that’s perhaps inevitable when few people would have it as their first choice. And it’s not like Cleveland is a very appealing city, especially for someone from CA.
There have been reports on CC that if waitlisted high stat students say “I’ll attend if you admit me” then it’s easy to get them to agree. So my guess is that the 1520 comes at least partially from those people.
Certainly Case rejects some high stats students, and makes others go through weird machinations, but chancing is about predicting odds. Even with an 80% chance of a positive outcome, the opposite occurs one out of five times. Outliers will defy the odds.
@AustenNut, whose posts I enjoy and respect, gave the OP less than a 50% chance of admission, even though the OP has a high GPA and SAT, plus strong ECs.
With and acceptance rate of 26%, 5 times that of the highly rejective schools like Stanford and Harvard, 2 out of 3 accepted students in the top 10% of their class, 16% of accepted students having a 4.0, and the 75th SAT percentile of 1520, something weird would have to happen for this OP to be rejected.
With an accepted student profile like they do, they admitted a LOT of high stats students.
Chancing is a bit of a silly game. It’s simply my opinion that the OP is a match for Case Western. Is that a guarantee that they’ll get in? No. It’s about the odds, not the outcome. The only way you can explain lower odds than that is yield protection, which has to be the exception to the rule based on their CDS numbers.
Back to our regularly scheduled programming. 
Or holistic admission.
Sure, but we’re talking odds here. According to their 2021-22 CDS, they admitted 10049 students with just below 16% yield. With a 75th percentile SAT of 1520, that means they admitted 2512 students with an SAT in the 99th percentile. That’s a lot of high stats students. I’m simply looking for evidence to support calling Case, a selective, but not highly rejective school, with record of admitting high stats students, a reach for a student that falls at the higher end of the applicant pool.
It cannot be assumed that the SAT distribution of enrolled students is the same as for admitted students, especially if one considers the separate ED-1, ED-2, EA, and RD admission pools.
If anything, our experience at the CWRU admitted students event was the opposite. High stats STEM students without the ECs to succeed in holistic UC admissions.
I didn’t. I’m sure though there are differences in acceptance rates between ED-1, RD and everything in between.