Necessity of Calculus

Is it absolutely necessary to take one semester of calc + semester of stats to get into UCI for Major in BIOSCI. I can handle two semesters of stats but am very weak in calculus and will likely hurt my gpa

IMHO If you are looking to pursue a BS degree in any field, Calculus is important.

Khan Academy has a great series on it here:

https://www.khanacademy.org/math/calculus-1

UCI’s School of Biological Sciences requires calculus (and physics that has a calculus prerequisite) as a graduation requirement. So, even if they admit you without it, you will have to take it some time.
http://catalogue.uci.edu/schoolofbiologicalsciences/#schoolrequirementstext

YouTube has some great resources too the organic chemistry guy and Patrick jmt are good for calc

their admission page doesn’t say calculus is required for xfer admission

However to be on the safe side you should ask admissions directly. Contact them via https://admissions.uci.edu/contact/index.php