<p>itz9001:
You are asking really good questions. Unfortunately some of what sschoe2 has to say in reply about the state of affairs in chemistry is true. However I think that he or she is very jaded about past work experiences and that is being reflected in the pessimism you read. Let’s start with the bad news first. From my perspective of almost 30 years in the biotech and pharmaceutical industry, I will be honest and state flat out that I have not experienced a worst time for this industry. Yes job openings are greatly reduced compared to the boom days of the 90’s. But put that in perspective-American industry in general is going through the same downturn. The kind of chemistry that I do-medicinal/organic chemistry- is being outsourced to China and India at a disturbing pace. And continued consolidation of the industry only decreases the kind of competition which drives an upward trend in employment rates.</p>
<p>So with all those negatives, I will argue why I think that sschoe2 sounds like a jilted lover to me and why I think that there still is hope in the pharma world. My own career story might be informative. When I came out of grad school in the early 80’s, it was a similar situation though not quite so bad. Pharma was not hiring, so I took a post doc. After the post doc, hiring was picking up, but I did not have the right skill set, so I took a job in a small biotech. I gained the right skills, and eventually obtained a position with a major pharmaceutical company where I been very successful. As you might guess, I am not one who gives up when presented with obstacles to attaining my goals. My message to you is to follow your dreams, and don’t let anybody’s pessimism stop you in your own pursuit.</p>
<p>As an optimist at heart, I refuse to believe that this downturn can go on forever. For one, I think the era of consolidation is finally over (at least I hope so!!). Pfizer has proven that that business model is a failure. But the reality of globalization is here, and no matter what you decide to do, you must factor that into your career decisions. There must continue to be a place for a strong pharma industry. If you are going to play in that game though, you must prepare yourself adequately. Number 1, excel at your studies. Number 2, do as much independent undergraduate research as you can. Find a professor at your school with an active graduate research program who will take you into his/her group. Wash dishes, do routine reactions, help a graduate student…do whatever it takes. Eventually you will do your research and that will be invaluable. Number 3, when you graduate with top grades and research experience under your belt, grad school is probably going to be mandatory. Because of the nature of the industry, an MS degree is desirable. (By the way, I am a PhD. But I think that today an MS is the way to go. That can the topic of another discussion.). Take the same work ethic through grad school and you will find a good job. Biotech is probably where you will start, but those companies often come and go, so you will have to nimble. I suggest targeting an area like Boston/Cambridge where there are many companies to which you can potentially jump if necessary.</p>
<p>Consider seriously other important functions in the pharma world which require a BS chemistry background. For example, pharmacology, the study of the fate of drugs in the body, is a very interesting area and may be less prone to outsourcing. And analytical chemistry, despite some negative comments above, is a versatile degree you can take into many different industries. Talk to as many professors and chemists in the fields that interest you. A good place to find a variety of chemistry professionals is the local American Chemical Society chapter. I can guarantee you that you will find many like myself who would be willing to discuss career options with you.</p>
<p>Two last items-First, you asked about working in between undergrad and grad school. This is an excellent option if you can find the right position with your BS degree. I know of a number of good BS chemists who absolutely excelled at grad school after having worked for a few years in pharma as lab associates. Second, IF your goal is to be a medicinal chemist (which is an organic chemist who synthesizes new compounds as potential drug candidates), DO NOT go to graduate school in a Medicinal Chemistry program. Instead, obtain your graduate degree in synthetic organic chemistry working with a high profile and highly regarded organic chemistry professor. This is very important in obtaining employment in the pharma industry. It’s a small world, and the grad program you come from and who you worked with makes a lot of difference.</p>
<p>Good luck, and stay focused on your goals.</p>