Will two Cs ruin my chances?

Hey everyone, So I’m a junior in high school and I’m kind of scared. This past semester I got all As except for a C+ in AP Calc AB and and AP Chem. My unweighted GPA will still be relatively high if I get straight As next semester(3.88). I’m just wondering, will colleges look down on my Cs and not consider me or will they look at my statistics and see these two Cs as outliers? Here are my stats for reference:

GPA(UW):3.88(potentially)
GPA(W):5.24(my school has a weird weighting scale)
Class Rank: 17/989
ACT:36

AP exams: Psych-5
US History-5
Statistics-4
Chem-4 or 5(our class is really difficult)
Calc AB-4 or 5
Micro-5
Macro-5
Lang and Comp-5
European History-5

If I get 4s or 5s on all my AP exams this year, I will be a National Scholar before my senior year, I’m not sure how beneficial that is to me.

ECs: Engineering Club:Founder and Vice President(120 members)
Model United Nations:President and Organizer of 200 person conference
Science National Honor Society-Chemistry Tutoring Chair(Ironically enough lol)
Amnesty International:President
Speech and Debate: Community/Outreach Officer and Event Leader

Special Awards: National Merit Commended/possible SF
AP National Scholar
State Finalist in Speech and Debate(top 6 out of 300)

In terms of my course rigor, in addition to the 6 APs I’m taking this year, I’m taking 3 classes at a local community college so my rigor is very very intense.

I’m just really worried if the Cs will ruin my chances at my dream schools considering the rest of my application. The schools I’d like to go to are: University of Michigan(ideally)
Purdue
Georgia Tech
Vanderbilt
Ohio State
Thanks a lot guys.

If you are getting C’s in calculus you might consider whether engineering is the career for you. Chemistry will not matter as much. Michigan engineering’s average GPA is 3.9 and average ACT is 33 so you are still above average even with the C. Vanderbilt really likes high test scores, as does GT. Purdue and OSU have lower stat admission averages than the others. Good luck next semester!