AP Bio or AP Chem for a potential microbiology/biochemistry major???

I am trying to choose between the 2 for my senior year since I do not have enough room to put both in. Feeling like both potential majors focus a lot on chemistry (esp. organic chemistry), but they also focus on biology too. Which ap class will help me more in the long run?

It does not matter. In college, you’ll need both. For senior year, pick the better teacher or the one that has the better AP test results, or the parameter of your choice. There is no wrong answer.

As a Microbiology major whom had to take 3.5 years of Chemistry in College, I would probably lean towards AP Chem. Only needed 1 extra quarter of PChem to get my minor.

Either would be fine, but my choice would depend on what credits I wanted. As a bio major, it’s nice to test out of general chem (at least in theory). That said, if you are not strong in chem, taking general chem in college is helpful before you move to orgchem, biochem, and pchem. If you are fairly confident in your chem skills, getting the bio credits mean more room in your schedule for upper level bio classes. This is speaking as a former bio major with micro concentration (no micro minor offered when I was in college) and chemistry minor working as a microbiologist.

if chem is more difficult for me, would it be better to take apchem right now to get the credits and understanding needed for college then?

If chem is weaker, I would take that in college. An AP science class may not (depending on the college) be as rigorous as the college equivalent and the college course may better prepare you (or provide a better foundations) for orgo, pchem, biochem.

Both are core courses that you will use, and you’ll likely have several follow-on courses in both areas, reading between the lines of your intend major.

Take whichever interests you most and will be most enjoyable. You’ll likely do better.

OP, you’ve taken both bio and chem already? (And physics?)
If so, agree with skieurope: either.

Now’s not the time to worry about college credit.