Chances for student on the rise?

<p>My brother will just be ending his junior year, and here's his stats. </p>

<p>3.3 GPA (UW)
18 ACT (Yikes!)
Won some academic awards.
Community service at local food pantry.
2 teacher recommendations</p>

<p>Started out with a GPA in the 2.8-3.0 range, but all of a sudden his junior year he's made a 4.0 both semesters.</p>

<p>Wants to major in Biology and go to either a Big12 or Big 10 school.</p>

<p>Where should he apply, and what would be his reaches, safeties, and matches?</p>

<p>Thanks</p>