Choosing A College- UMass vs USF

So, I am from California and I really was hoping to go to a UC (especially UCSB) but I have been rejected from UCLA, UCSD, UCD, and UCSB so far and I have been feeling so bad for myself. I am a very academically strong student but guess not good enough for a UC.
SO, i decided to get realistic. I need to think where to go and I am stuck between UMass Amherst versus University of South Florida Honors College as I got admitted into both schools. I applied under a molecular biology major and want to hear input on which college has a better program . I might try transferring to UCSB after 1 year but I also might stay. I just want to go to a good academically strong college where I can feel safe and succeed academiccaly and pursue my dream to go to med school.
Appreciate information from people who go to these colleges.