Hi, I’m at the end of a really bad week in college (I’m a freshman at private liberal arts school) and I’m just not sure what my next step is. At the beginning of the week it was okay, because I had gone to some meetings on maybe participating in deferred rush, and met some really nice new people. But all week I’ve felt sick, and then this is all following my roommate suddenly moving out and becoming a commuter two weeks ago, and only telling me the day before she moved out. Things have been really weird with her, and then yesterday some more weird stuff happened with her and it kind of sent me over in terms of the amount of stress I’ve had. I talked to my mom about it, and she offered for me to come home this weekend (I’m about an hour and half away). I really really want to go home, because all of a sudden I’ve started feeling really hopeless here, but this week is Halloween and Homecoming, and even though I don’t really party or was super looking forward to it, I feel a bad leaving because everyone I know has been hyping it up. Would it be terrible if I left for the weekend?
PS It’s been about two and half weeks since Fall Break, which was the last time I went home. I haven’t been thrilled here, but I have people I’m friendly with in all my classes and some people that I can hangout with on the weekends. Despite this, I feel really isolated from my hall mates because they party all the time and I don’t. I thought we were fine even though we aren’t close but a few weeks ago I heard them talking about me outside in the hall. I don’t know, this has been the first time I’ve just felt terrible about being here. I almost started crying in one of my classes this morning.
So I would say, give it some time. Freshman year of college is a big adjustment. I tell folks invariably one or all of 4 things happen first semester freshman year: roommate issues, getting mono or the flu, taking on too much academically and feeling overwhelmed, or a relationship break-up.
Since you are so close to home, it it helps to get support from your family (and it probably will), plan to get home for part of it.
Ultimately, you want to keep developing relationships at school so it starts to feel like home, so plan to spend some time of the fun weekend with classmates, dormmates or friends. That’s my two cents!
It will get better. Making genuine friendships take time. Allow yourself more time and keep telling yourself things will get better, because they absolutely will! 
I will give you the same advice I gave my daughter. Stop worrying about what others think. If you truly need to go home for whatever reason then go. However going home on weekends will make it tougher to connect with others. So be honest with yourself about if you truly need to go home. Going home to avoid dealing with issues might not be the best answer since they will still be there when you go back. Going home when you are reaching your breaking point can often be a life saver.
You seem be to looking forward to this weekend. You had some serious unexpected stressors this week but you also have what appears to be a fun weekend to distress with. Only you can determine what is best for you. Either way, leave the guilt behind. It is important to do what is best for you.
Regarding your roommate, if she is moving home to be a commuter, it is likely because she is having her own issues or rough time. It is not a reflection on you at all.
First semester is tough for most kids. Even though they may not show it on the outside, most have their own set of insecurities they are dealing with as a college freshman, some just do a better job of masking it. Regarding your hall, there is a tendency to hang out with hall mates in the beginning, because those are the people you see the most. But it is a random thing, and a lot of times, hall mates don’t end up being the best of friends. I bet by the end of the yr, you will see that some of these groups of friends have dissolved. It is normal to feel hopeless, but please don’t give up. Perhaps talk to your RA. She likely knows other girls who feel the exact way you do.