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<p>That depends on how long after the drinking you take the pain reliever, and whether or not you’re planning on doing any more drinking later that day! </p>
<p>[Combining</a> Tylenol, alcohol can result in serious consequences](<a href=“http://www.olemiss.edu/news/dm/archives/97/9710/971006/971006N2alcohol.HTML]Combining ”>http://www.olemiss.edu/news/dm/archives/97/9710/971006/971006N2alcohol.HTML )</p>
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“The vast majority of people get away with (mixing pain relievers and alcohol),” Dahl said. “You can’t predict who will have what response.”
Dahl says that after consuming alcohol, as a general rule, one should avoid taking Tylenol or an ibuprofen such as Advil for six hours, depending on whether the alcohol was taken on an empty stomach and the amount of alcohol consumed.
At the FDA panel hearings on acetaminophen, an expert testifying for the makers of Advil said that individuals who drink more than two alcoholic beverages a day should not take more than two grams of acetaminophen a day. The makers of Tylenol pointed out that ibuprofen can cause gastrointestinal bleeding in heavy drinkers.
“Both (Advil and Tylenol) are wonderful drugs with a safety profile that is terrific,” Dr. David Katzka, a gastroenterologist at the University of Pennsylvania School of Medicine said in a 1996 New York Times article. “It is only a very small minority of people who take the drugs and have serious side effects. Gastrointestinal bleeding associated with ibuprofen is a more common problem, but the severe liver toxicity you get in rare cases with acetaminophen is more serious.”
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