What is a bad grade for senior year?

I am currently taking AP Calculus BC, APES, AP French, AP Computer Science, AP Economics, an honors science course, regular english, and gym.

So far, I have been able to maintain B’s or higher in all of my classes except AP CompSci, which I am struggling. If I get a C+, in only that class, would that hurt my chances into getting into a good school? I plan on applying to Cornell, but other than that mainly just schools ranked around 25-50 on USNews.